Stacky5's Southwest Tuna Macaroni & Cheese Casserole

Prep Time
Cook Time
1h 15m
Ready In


Original recipe yields 4 servings


  • Serving Size: 1 (339 g)
  • Calories 609.3
  • Total Fat - 28.3 g
  • Saturated Fat - 11.4 g
  • Cholesterol - 53.9 mg
  • Sodium - 1937.8 mg
  • Total Carbohydrate - 62.8 g
  • Dietary Fiber - 2.9 g
  • Sugars - 8.5 g
  • Protein - 26.5 g
  • Calcium - 459.8 mg
  • Iron - 2.1 mg
  • Vitamin C - 1.4 mg
  • Thiamin - 0.2 mg

Step 1

Cook macaroni according to package directions to "al dente",

Step 2

Then drain and rinse with cool water, and let drain again.

Step 3


Step 4

Combine soup, mayonnaise and milk,

Step 5

And stir until smooth.

Step 6

Preheat oven to 350 degrees,

Step 7

And slightly grease a 2 quart glass baking dish.

Step 8

Mix macaroni, soup mixture, jack cheese,salsa, salt & pepper, and flaked tuna thoroughly in a large bowl.

Step 9

Pour mixture into baking dish,

Step 10

Sprinkle bread crumbs evenly on top,

Step 11

And then dot with margarine on top.

Step 12

Bake, uncovered at 350 degrees for 30 minutes.

Tips & Variations

No special items needed.



Made this for the hubby and he reported back that this is the best tuna casserole he's ever had...he loved the creaminess of the dish and the flavors...he went back for seconds...and there's plenty of leftovers for him...I used home canned albacore tuna...made for "Bill Board" tag game...

review by:
(23 Jan 2016)


My whole family loved this casserole, I did make a change and used cooked chicken in place of tuna, I've done that before with success next time I will use tuna, I also used small shell pasta instead of macaroni because that's what I had, the adddition of salsa really jazzes it up, I have this now added to my Recipebook favorites and I will make it again for sure many more times, so thanks dieniab for the recipe.

review by:
(12 May 2015)