Mexican American Lasagna

Prep Time
Cook Time
Ready In

"A crowd pleasing lasagna with Mexican flavors."

Original is 12 servings


  • Serving Size: 1 (283.2 g)
  • Calories 337.7
  • Total Fat - 18.9 g
  • Saturated Fat - 9.1 g
  • Cholesterol - 68.4 mg
  • Sodium - 665.2 mg
  • Total Carbohydrate - 17.6 g
  • Dietary Fiber - 4.1 g
  • Sugars - 6 g
  • Protein - 25.3 g
  • Calcium - 421.9 mg
  • Iron - 2.6 mg
  • Vitamin C - 16.3 mg
  • Thiamin - 0.2 mg

Step by Step Method

Step 1

In a Dutch oven, cook beef and onion over medium heat until meat is no longer pink; drain. Stir in the beans, tomatoes, salsa, chilies and seasonings.

Step 2

In a large bowl, combine Monterey Jack and mozzarella cheeses; set aside 1 cup. Stir cottage cheese and 3/4 cup sour cream into remaining cheese mixture.

Step 3

Spread 1 cup meat sauce into a greased 13-in. x 9-in. baking dish. Layer with three noodles, and a third of the cottage cheese mixture and meat sauce. Repeat layers twice (dish will be full).

Step 4

Cover and bake at 350° for 1 hour. Uncover; spread with remaining sour cream. Sprinkle with reserved cheeses. Bake 10-12 minutes longer or until cheese is melted. Let stand for 10 minutes before serving.


No special items needed.

Editorial Notes

The ingredient tips, suggestions, variations, facts, questions and answers below are not edits to the original author's recipe. They are not meant to imply any change would improve the recipe. They're offered for convenience, alternative ideas, and points of interest. If you have any comments about them, please post in the Help & Ideas forum.

  • For a spicier lasagna, try using medium or hot chili beans instead of mild chili beans.
  • If you don't have taco seasoning, you can use your own combination of chili powder, cumin, garlic powder, oregano, and salt.

  • Ground turkey instead of ground beef: Ground turkey is a healthier option than ground beef, and it will still provide the same flavor and texture to the dish.
  • Cheddar cheese instead of Monterey Jack cheese: Cheddar cheese is a bit sharper and more flavorful than Monterey Jack cheese, so it will add a bit more of a kick to the dish.

Vegetarian Lasagna Replace the ground beef with 1 package (12 ounces) frozen vegetarian burger crumbles. Use vegetable broth instead of beef broth. Add 1/2 cup sliced black olives to the cottage cheese mixture and use 1/2 cup salsa instead of 1 cup.

Mexican Street Corn Salad - A delicious side dish that complements the Mexican flavors of the lasagna. The creamy, tangy dressing and the crunch of the corn make it a perfect accompaniment.

: Mexican Rice:

: Mexican Rice is the perfect accompaniment to the Mexican Lasagna. It is a simple yet flavorful side dish that adds a nice contrast to the rich flavors of the lasagna. The rice is cooked in a flavorful tomato sauce and seasoned with garlic, cumin, and chili powder, making it the perfect compliment to the Mexican Lasagna.


Q: How long should I bake the lasagna?

A: Bake the lasagna covered for 1 hour, and then uncovered for an additional 10-12 minutes or until the cheese is melted. Let stand for 10 minutes before serving.

Q: What ingredients do I need for lasagna?

A: You will need lasagna noodles, Italian sausage, ricotta cheese, mozzarella cheese, Parmesan cheese, tomato sauce and seasonings.

2 Reviews


This makes a lot and is easy to make. I thought I had the can of tomatoes, but I didn't. I replaced them with a Roma tomato and a can of tomato paste. I poured salsa over the top when I ate it.


(29 May 2022)

Daily Inspiration

Great flavor and although there are quite a few ingredients, it comes together easily. Next time I would halve the recipe as this makes a lot. Although, leftovers sound really good to me. The only change I made was to use the oven ready lasagna noodles and they turned out well for this dish.


(21 Jan 2021)

You'll Also Love

Fun facts:

The Mexican American Lasagna recipe is a great way to combine two cultures in one dish. It was popularized by the famous chef and TV personality, Martha Stewart, who often featured the recipe on her show.

The combination of Mexican and American flavors in this lasagna recipe is said to have originated in the 1940s by the famous Mexican-American singer and actress, Carmen Miranda. She was known for her style of combining Latin American and American music and cuisine.