Step 1: Heat oil in a large skillet pan over medium-low heat. Add onion, bell pepper, garlic, and oregano. Season with salt and pepper. Cook, stirring occasionally, until softened, 8 to 10 minutes.
Step 2: Increase heat to medium. Add beef and season with salt and pepper. Cook, breaking beef up with a spoon and stirring occasionally, until brown, 5 to 6 minutes.
Step 3: Stir in ketchup, beer, Worcestershire, tomato paste, sugar, and chile powder. Reduce heat to medium-low and simmer until sauce has thickened, 15 to 20 minutes.
Step 4: Serve on buttered, toasted buns.
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