Step 1: Sift the confectioners' sugar into a large bowl; set aside.
Step 2: Grease a 9-inch square pan; line with plastic wrap.
Step 3: Combine brown and granulated sugars in a medium saucepan with the butter and milk.
Step 4: Heat over medium heat, stirring, until blended and butter is melted.
Step 5: Bring to a full boil; continue boiling, stirring occasionally, for 5 minutes.
Step 6: Quickly stir in the vanilla, peanut butter, and marshmallow creme; pour over the confectioners' sugar and stir to mix well.
Step 7: Spoon into the prepared pan. Cover with plastic wrap, pat down to level out and chill until firm.
Step 8: Cut into squares when firm.
Step 9: If the fudge is difficult to cut, let it stand at room temperature for 15 to 20 minutes before cutting.
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