Step 1: Preheat your oven to 400°F (200°C). Line a baking sheet with parchment paper or lightly grease it.
Step 2: In a small bowl, whisk together the soy sauce, honey, lime juice, sesame oil, minced garlic, grated ginger, red pepper flakes (if using), salt, and pepper.
Step 3: Place the tilapia fillets on the prepared baking sheet. Pour the marinade mixture over the fillets, ensuring they are evenly coated. Reserve some marinade for basting later.
Step 4: Bake the tilapia in the preheated oven for about 12-15 minutes, or until the fish is cooked through and flakes easily with a fork. Baste the fillets with the reserved marinade halfway through the cooking time.
Step 5: Once cooked, remove the tilapia from the oven and let it rest for a few minutes.
Step 6: Transfer the tilapia fillets to serving plates. Garnish with sliced green onions and fresh cilantro.
Step 7: Serve with lime wedges on the side.
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