Step 1: Preheat oven to 350 degrees F then line 24 regular-size muffin tins with paper liners.
Step 2: In a large bowl, cream butter and sugar until light and fluffy. Add eggs, one at a time beating well after each addition, then beat in vanilla and pumpkin until combined.
Step 3: In a bowl combine the flour, pie spice, baking powder, cinnamon, salt, baking soda and ginger; add to the creamed mixture alternately with buttermilk, beating well after each addition.
Step 4: Divide into muffin tins about 3/4 full. Bake at 350° for 20-25 minutes or until a toothpick inserted in the center comes out clean. Cool for 10 minutes before removing from pans to wire racks to cool completely.
Step 5: Bake 20-25 minutes or until a toothpick inserted in the center comes out clean; cool for 10 minutes before removing from pans to wire racks to cool completely.
Step 6: Frost with cream cheese frosting.
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