Step 1: Preheat oven to 375°F.
Step 2: Melt butter in heavy saucepan over medium-low heat.
Step 3: Whisk in flour.
Step 4: Cook, whisking, 3 minutes.
Step 5: Whisk in milk and simmer, stirring about 8 minutes.
Step 6: In bowl, whisk eggs.
Step 7: Add 1 cup of milk mixture in a steady stream, whisking constantly to keep eggs from cooking.
Step 8: Whisk egg mixture into remaining milk mixture and stir in seasonings. Cover surface with plastic wrap and keep warm.
Step 9: Cook penne in boiling salted water until al dente.
Step 10: Rinse and drain well.
Step 11: Combine pot roast, broth and gravy in a large bowl.
Step 12: Butter a shallow 7"x11" baking dish.
Step 13: Place half of pasta evenly over the bottom of dish.
Step 14: Top with 1/3 cup of sauce.
Step 15: Spread beef mixture evenly over pasta.
Step 16: Top with remaining pasta.
Step 17: Pour remaining sauce SLOWLY over pasta.
Step 18: Bake for about 20 minutes.
Step 19: Top with cheese and bake until set, about 20 minutes more.
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