Step 1: Preheat oven to 350°F. Line 12-cup muffin pan with paper liners.
Step 2: Sift flour, sugar, cocoa, baking soda, baking powder, and salt in large bowl. Stir beet puree, oil, egg, vanilla, and buttermilk together in small bowl. Stir in dry ingredients until combined. Divide among 12 cups.
Step 3: Bake until wooden pick inserted in center comes out clean, about 16 minutes. Cool completely.
Step 4: Beat sugar, cream cheese, butter, 1 Tbsp beet puree, and vanilla until smooth and fluffy. Spread over cupcakes.
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